Department of Internal Medicine and Molecular and Integrative Physiology, Division of Nephrology, University of Michigan, Ann Arbor, MI, United States. Department of Neurology, University of Michigan, Ann Arbor, MI, United States. Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States. Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI, United States. Department of Radiology, Division of Nuclear Medicine, University of Michigan, Ann Arbor, MI, United States. Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, United States. Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, MI, United States. Electronic address: rpbusui@umich.edu.